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Article

CYP2C gene polymorphisms in North African populations.

Molecular biology reports - 12 Nov 2024

Messaoudi Mohsen, Pakstis Andrew J, Boussetta Sami, Ben Ammar Elgaaied Amel, Kidd Kenneth K, Cherni Lotfi

Abstract excerpt

BACKGROUND: Cytochrome P450 is a superfamily of genes generating hemoproteins that metabolize foreign chemicals as well as endogenous compounds, such as steroids. The human CYP2C genes (CYP2C8, CYP2C9, CYP2C18, CYP2C19) cluster on chromosome 10 and metabolize many clinically useful drugs. CYP2C19 and CYP2C9 have been the most studied while CYP2C8 has been studied less frequently. CYP2C18 has been relatively...

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PMID: 39532754
DOI: 10.1007/s11033-024-10093-8

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