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Article

Association of SORL1 gene variants with Alzheimer's disease.

Brain research - 6 Apr 2009

Kölsch Heike, Jessen Frank, Wiltfang Jens, Lewczuk Piotr, Dichgans Martin, Teipel Stefan J, Kornhuber Johannes, Frölich Lutz, Heuser Isabella, Peters Oliver, Wiese Birgitt, Kaduszkiewicz Hanna, van den Bussche Hendrik, Hüll Michael, Kurz Alexander, Rüther Eckhart, Henn Fritz A, Maier Wolfgang

Abstract excerpt

SORL1 gene variants were described as risk factor of Alzheimer's disease (AD) additionally SORL1 gene variants were associated with altered Abeta(42) CSF levels in AD patients. In the present study we investigated the association of SORL1 gene variants (rs2070045 (SNP19), SORL1-18ex26 (SNP21), rs3824968 (SNP23), rs1010159 (SNP25)) with AD risk by using Cox proportional hazard model and Kaplan-Meier survival...

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Source

Identifiers

PMID: 19368828
DOI: 10.1016/j.brainres.2009.01.044

Genes

SORL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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