Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SORL1 Variants Show Different Association with Early-Onset and Late-Onset Alzheimer's Disease Risk.

Journal of Alzheimer's disease : JAD - 1 Jan 2017

Liu Guiyou, Sun Jing-Yi, Xu Meiling, Yang Xiao-Yi, Sun Bao-Liang

Abstract excerpt

A recent study sequenced the full coding region of SORL1 in 1,255 early-onset Alzheimer's disease (EOAD) cases and 1,938 control individuals, and investigated the contribution of genetic variability in SORL1 to EOAD risk in a European cohort. This study identified six common variants and five low frequency variants in the SORL1 coding sequence. However, none of these 11 variants was significantly associated with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Alzheimer Disease
Share to Databases, Factual

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genome-Wide Association Study

Share to LDL-Receptor Related Proteins

Share to Membrane Transport Proteins

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 28527213
DOI: 10.3233/JAD-170005

Genes

SORL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SORL1 Variants Show Different Association with Early-Onset and Late-Onset Alzheimer's Disease Risk.PMID 28527213Read ↗

The Alzheimer's associated 5' region of the SORL1 gene cis regulates SORL1 transcripts expression.Semantic proximity Read ↗

SORL1 rare variants: a major risk factor for familial early-onset Alzheimer's disease.Semantic proximity Read ↗

SORL1 variants and risk of late-onset Alzheimer's disease.Semantic proximity Read ↗

SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians.Semantic proximity Read ↗

SORL1 is genetically associated with neuropathologically characterized late-onset Alzheimer's disease.Semantic proximity Read ↗

SORL1 variants across Alzheimer's disease European American cohorts.Semantic proximity Read ↗

SORL1 Polymorphisms in Mexican Patients with Alzheimer's Disease.Semantic proximity Read ↗

Novel Rare SORL1 Variants in Early-Onset Dementia.Semantic proximity Read ↗

The genetic variation of SORCS1 is associated with late-onset Alzheimer's disease in Chinese Han population.Semantic proximity Read ↗

Association between SORL1 and Alzheimer's disease in a genome-wide study.Semantic proximity Read ↗

Heterozygous and Homozygous Variants in SORL1 Gene in Alzheimer's Disease Patients: Clinical, Neuroimaging and Neuropathological Findings.Semantic proximity Read ↗

No association of SORL1 SNPs with Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.