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Article

Influence of SORL1 gene variants: association with CSF amyloid-beta products in probable Alzheimer's disease.

Neuroscience letters - 25 Jul 2008

Kölsch Heike, Jessen Frank, Wiltfang Jens, Lewczuk Piotr, Dichgans Martin, Kornhuber Johannes, Frölich Lutz, Heuser Isabella, Peters Oliver, Schulz Jörg B, Schwab Sibylle G, Maier Wolfgang

Abstract excerpt

SORL1 gene variants were described as risk factors of Alzheimer's disease (AD). We investigated the association of four SORL1 variants with CSF levels of Abeta42 and Abeta40 in 153 AD patients recruited from a multicenter study of the German Competence Net Dementias. Only one SORL1 SNP was associated with altered Abeta42 levels in the single marker analysis (SNP21: p=0.011), the other SNPs did not show an...

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Source

Identifiers

PMID: 18541377
DOI: 10.1016/j.neulet.2008.05.049

Genes

SORL1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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