Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between SORL1 and Alzheimer's disease in a genome-wide study.

Neuroreport - 19 Nov 2007

Meng Yan, Lee Joseph H, Cheng Rong, St George-Hyslop Peter, Mayeux Richard, Farrer Lindsay A

Abstract excerpt

Several studies have reported an association of Alzheimer's disease (AD) with polymorphic markers in SORL1. Data from a recently published genome-wide association study in AD have been made publicly available. We tested the association of AD with SORL1 in this dataset (Translational Genomics Research Institute; TGEN), which included 31 SORL1 single nucleotide polymorphisms (SNPs), eight of which overlapped the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Databases, Genetic
Share to Europe

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genome, Human

Share to LDL-Receptor Related Proteins

Share to Linkage Disequilibrium

Share to Membrane Transport Proteins

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 18090307
DOI: 10.1097/WNR.0b013e3282f13e7a
PMCID: PMC2631643

Genes

SORL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between SORL1 and Alzheimer's disease in a genome-wide study.PMID 18090307Read ↗

Heterozygous and Homozygous Variants in SORL1 Gene in Alzheimer's Disease Patients: Clinical, Neuroimaging and Neuropathological Findings.Semantic proximity Read ↗

Down-regulation of SORL1 is associated with Alzheimer's disease through activating ABC transporter pathway.Semantic proximity Read ↗

SORL1 Variants Show Different Association with Early-Onset and Late-Onset Alzheimer's Disease Risk.Semantic proximity Read ↗

The Role of SORL1 in Alzheimer’s DiseaseSemantic proximity Read ↗

Identification and description of three families with familial Alzheimer disease that segregate variants in the SORL1 gene.Semantic proximity Read ↗

Association between genetic variants in SORL1 and autopsy-confirmed Alzheimer disease.Semantic proximity Read ↗

The association between genetic variants in SORL1 and Alzheimer disease in an urban, multiethnic, community-based cohort.Semantic proximity Read ↗

A familial missense variant in the Alzheimer's disease gene SORL1 impairs its maturation and endosomal sorting.Semantic proximity Read ↗

SORL1 is genetically associated with increased risk for late-onset Alzheimer disease in the Belgian population.Semantic proximity Read ↗

Characterization of pathogenic SORL1 genetic variants for association with Alzheimer's disease: a clinical interpretation strategy.Semantic proximity Read ↗

Meta-analysis of the association between variants in SORL1 and Alzheimer disease.Semantic proximity Read ↗

Novel Rare SORL1 Variants in Early-Onset Dementia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.