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Article

Novel Rare SORL1 Variants in Early-Onset Dementia.

Journal of Alzheimer's disease : JAD - 1 Jan 2021

Korpioja Anita, Krüger Johanna, Koivuluoma Susanna, Pylkäs Katri, Moilanen Virpi, Helisalmi Seppo, Hiltunen Mikko, Remes Anne M

Abstract excerpt

BACKGROUND: Rare variants of SORL1 have been associated with an increased risk of early-onset or late-onset Alzheimer's disease (AD). However, a lot remains to be clarified about their significance in the pathogenesis of the disease. OBJECTIVE: To evaluate the role of SORL1 variants among Finnish patients with early-onset AD (EOAD). METHODS: The rare SORL1variants were screened in a cohort of 115 Finnish EOAD...

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PMID: 34092641
DOI: 10.3233/JAD-210207

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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