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Article

Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23.

Human molecular genetics - 15 Jul 2009

Orozco Gisela, Hinks Anne, Eyre Steve, Ke Xiayi, Gibbons Laura J, Bowes John, Flynn Edward, Martin Paul, Wilson Anthony G, Bax Deborah E, Morgan Ann W, Emery Paul, Steer Sophia, Hocking Lynne, Reid David M, Wordsworth Paul, Harrison Pille, Thomson Wendy, Barton Anne, Worthington Jane

Abstract excerpt

The most consistent finding derived from the WTCCC GWAS for rheumatoid arthritis (RA) was association to a SNP at 6q23. We performed a fine-mapping of the region in order to search the 6q23 region for additional disease variants. 3962 RA patients and 3531 healthy controls were included in the stu...

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Identifiers

PMID: 19417005
DOI: 10.1093/hmg/ddp193
PMCID: PMC2701332

Genes

TNFAIP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19417005-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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