Article
Rheumatoid arthritis-associated polymorphisms at 6q23 are associated with radiological damage in autoantibody-positive RA.
The Journal of rheumatology - 1 Sept 2012
Maxwell James R, Marinou Ioanna, Kuet Kar-Ping, Orozco Gisela, Moore David J, Barton Anne, Worthington Jane, Wilson A Gerry
Abstract excerpt
OBJECTIVE: Recent studies have identified 6q23 as an important susceptibility locus for rheumatoid arthritis (RA), with risk alleles at 3 single-nucleotide polymorphisms combining to give an effect size greater than that of these markers individually. We investigated whether these polymorphisms are also associated with disease severity measured by radiological damage. METHODS: We studied 927 patients from a...
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