Analysis of TNFAIP3, a feedback inhibitor of nuclear factor-kappaB and the neighbor intergenic 6q23 region in rheumatoid arthritis susceptibility.

doi:10.1186/ar2650

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Article

Analysis of TNFAIP3, a feedback inhibitor of nuclear factor-kappaB and the neighbor intergenic 6q23 region in rheumatoid arthritis susceptibility.

Arthritis research & therapy - 1 Jan 2009

Dieguez-Gonzalez Rebeca, Calaza Manuel, Perez-Pampin Eva, Balsa Alejandro, Blanco Francisco J, Cañete Juan D, Caliz Rafael, Carreño Luis, de la Serna Arturo R, Fernandez-Gutierrez Benjamin, Ortiz Ana Maria, Herrero-Beaumont Gabriel, Pablos Jose L, Narvaez Javier, Navarro Federico, Marenco Jose L, Gomez-Reino Juan J, Gonzalez Antonio

Abstract excerpt

INTRODUCTION: Genome-wide association studies of rheumatoid arthritis (RA) have identified an association of the disease with a 6q23 region devoid of genes. TNFAIP3, an RA candidate gene, flanks this region, and polymorphisms in both the TNFAIP3 gene and the intergenic region are associated with systemic lupus erythematosus. We hypothesized that there is a similar association with RA, including polymorphisms in...

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PMID: 19292917
DOI: 10.1186/ar2650
PMCID: PMC2688189

Genes

TNFAIP3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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