Article
Molecular analysis of the gyrA and gyrB quinolone resistance-determining regions of fluoroquinolone-resistant Clostridium difficile mutants selected in vitro.
Antimicrobial agents and chemotherapy - 1 Jun 2009
Spigaglia Patrizia, Barbanti Fabrizio, Louie Thomas, Barbut Frédéric, Mastrantonio Paola
Abstract excerpt
Recent studies have suggested that exposure to fluoroquinolones represents a risk factor for the development of Clostridium difficile infections and that the acquisition of resistance to the newer fluoroquinolones is the major reason facilitating wide dissemination. In particular, moxifloxacin (M...
Topics
- Aza Compounds
- Clostridioides difficile
- DNA Gyrase
- Drug Resistance, Bacterial
- Fluoroquinolones
- Gatifloxacin
- Levofloxacin
- Microbial Sensitivity Tests
- Moxifloxacin
- Mutation
- Ofloxacin
- Quinolines