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Article

Molecular analysis of the gyrA and gyrB quinolone resistance-determining regions of fluoroquinolone-resistant Clostridium difficile mutants selected in vitro.

Antimicrobial agents and chemotherapy - 1 Jun 2009

Spigaglia Patrizia, Barbanti Fabrizio, Louie Thomas, Barbut Frédéric, Mastrantonio Paola

Abstract excerpt

Recent studies have suggested that exposure to fluoroquinolones represents a risk factor for the development of Clostridium difficile infections and that the acquisition of resistance to the newer fluoroquinolones is the major reason facilitating wide dissemination. In particular, moxifloxacin (MX) and levofloxacin (LE) have been recently associated with outbreaks caused by the C. difficile toxinotype III/PCR...

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Identifiers

PMID: 19364867
DOI: 10.1128/AAC.01252-08
PMCID: PMC2687229

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Molecular analysis of the gyrA and gyrB quinolone resistance-determining regions of fluoroquinolone-resistant Clostridium difficile mutants selected in vitro.PMID 19364867Read ↗

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