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Article

In vitro assessment of the further potential for development of fluoroquinolone resistance in Neisseria meningitidis.

Antimicrobial agents and chemotherapy - 1 May 2005

Shultz Tiffany R, White Peter A, Tapsall John W

Abstract excerpt

We examined the potential for the development of fluoroquinolone resistance in Neisseria meningitidis by cultivating two clinical isolates of meningococci in the presence of concentrations of ciprofloxacin at and about the predetermined MIC. The quinolone resistance determining regions (QRDRs) of gyrA and parC of 50 stable quinolone-resistant mutants derived in vitro were sequenced and compared with QRDR...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 15855492
DOI: 10.1128/AAC.49.5.1753-1760.2005
PMCID: PMC1087667

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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