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Article

In vitro assessment of the further potential for development of fluoroquinolone resistance in Neisseria meningitidis.

Antimicrobial agents and chemotherapy - 1 May 2005

Shultz Tiffany R, White Peter A, Tapsall John W

Abstract excerpt

We examined the potential for the development of fluoroquinolone resistance in Neisseria meningitidis by cultivating two clinical isolates of meningococci in the presence of concentrations of ciprofloxacin at and about the predetermined MIC. The quinolone resistance determining regions (QRDRs) of...

Topics

Amino Acid Substitution
Anti-Bacterial Agents
DNA Gyrase
DNA Topoisomerase IV
DNA, Bacterial
Drug Resistance, Bacterial
Fluoroquinolones
Microbial Sensitivity Tests
Mutation
Neisseria meningitidis
Reverse Transcriptase Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15855492
DOI: 10.1128/AAC.49.5.1753-1760.2005
PMCID: PMC1087667

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-15855492-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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