Article
Resistance to moxifloxacin in toxigenic Clostridium difficile isolates is associated with mutations in gyrA.
Antimicrobial agents and chemotherapy - 1 Aug 2001
Ackermann G, Tang Y J, Kueper R, Heisig P, Rodloff A C, Silva J, Cohen S H
Abstract excerpt
Clostridium difficile is the etiological agent of antibiotic-associated colitis and the most common cause of hospital-acquired infectious diarrhea. Fluoroquinolones such as ciprofloxacin are associated with lower risks of C. difficile-associated diarrhea. In this study, we have analyzed 72 C. difficile isolates obtained from patients with different clinical courses of disease, such as toxic megacolon and...
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