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Article

In vitro-selected resistance to fluoroquinolones in two Brucella strains associated with mutational changes in gyrA.

International journal of antimicrobial agents - 1 Sept 2008

Turkmani Aun, Psaroulaki Anna, Christidou Athanasia, Chochlakis Dimosthenis, Tabaa Darem, Tselentis Yannis

Abstract excerpt

In the present study, Brucella melitensis biovar Abortus 2308 and Brucella abortus 3196 biotype 5 reference strains, which are susceptible to fluoroquinolones, became in vitro-resistant to fluoroquinolones by culture in trypticase soy agar. The quinolone resistance-determining regions (QRDRs) of the gyrA and parC genes of the two reference strains were analysed by polymerase chain reaction sequencing analysis to...

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PMID: 18583100
DOI: 10.1016/j.ijantimicag.2008.03.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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