Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In vitro-selected resistance to fluoroquinolones in two Brucella strains associated with mutational changes in gyrA.

International journal of antimicrobial agents - 1 Sept 2008

Turkmani Aun, Psaroulaki Anna, Christidou Athanasia, Chochlakis Dimosthenis, Tabaa Darem, Tselentis Yannis

Abstract excerpt

In the present study, Brucella melitensis biovar Abortus 2308 and Brucella abortus 3196 biotype 5 reference strains, which are susceptible to fluoroquinolones, became in vitro-resistant to fluoroquinolones by culture in trypticase soy agar. The quinolone resistance-determining regions (QRDRs) of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Brucella abortus
Share to Ciprofloxacin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Gyrase

Share to Fluoroquinolones

Share to Microbial Sensitivity Tests

Share to Ofloxacin

Share to Selection, Genetic

Source

Identifiers

PMID: 18583100
DOI: 10.1016/j.ijantimicag.2008.03.012

Genes

TAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18583100-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In vitro-selected resistance to fluoroquinolones in two Brucella strains associated with mutational changes in gyrA.PMID 18583100Read ↗

Comparison of gyrA gene mutations between laboratory-selected ofloxacin-resistant Mycobacterium tuberculosis strains and clinical isolates.Semantic proximity Read ↗

Fluoroquinolone-resistant Brucella melitensis mutants obtained in vitro.Semantic proximity Read ↗

High Proportion of Fluoroquinolone-Resistant Mycobacterium tuberculosis Isolates with Novel Gyrase Polymorphisms and a <i>gyrA</i> Region Associated with Fluoroquinolone SusceptibilitySemantic proximity Read ↗

Enhanced resistance to fluoroquinolones in laboratory-grown mutants & clinical isolates of Shigella due to synergism between efflux pump expression & mutations in quinolone resistance determining region.Semantic proximity Read ↗

Type II topoisomerase mutations in Bacillus anthracis associated with high-level fluoroquinolone resistance.Semantic proximity Read ↗

A novel gyrB gene mutation in fluoroquinolone resistant clinical isolates of Mycobacterium tuberculosisSemantic proximity Read ↗

In vitro assessment of the further potential for development of fluoroquinolone resistance in Neisseria meningitidis.Semantic proximity Read ↗

Sequence Analysis of Fluoroquinolone Resistance-Associated Genes <i>gyrA</i> and <i>gyrB</i> in Clinical Mycobacterium tuberculosis Isolates from Patients Suspected of Having Multidrug-Resistant Tuberculosis in New Delhi, IndiaSemantic proximity Read ↗

gyrA and gyrB gene mutation in ciprofloxacin-resistant Mycobacterium massiliense clinical isolates from Southern Brazil.Semantic proximity Read ↗

Molecular Characterization of Fluoroquinolone-Resistant Moraxella catarrhalis Variants Generated In Vitro by Stepwise Selection.Semantic proximity Read ↗

Salmonella typhimurium gyrA mutations associated with fluoroquinolone resistance.Semantic proximity Read ↗

Alterations in DNA gyrase and topoisomerase IV in resistant mutants of Clostridium perfringens found after in vitro treatment with fluoroquinolones.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.