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Article

gyrA and gyrB mutations are implicated in cross-resistance to Ciprofloxacin and moxifloxacin in Clostridium difficile.

Antimicrobial agents and chemotherapy - 1 Nov 2002

Dridi Larbi, Tankovic Jacques, Burghoffer Béatrice, Barbut Frédéric, Petit Jean-Claude

Abstract excerpt

A total of 198 nonrepetitive clinical strains of Clostridium difficile isolated from different French hospitals in 1991 (n = 100) and 1997 (n = 98) were screened for decreased susceptibility to fluoroquinolones by plating onto Wilkins-Chalgren agar containing 16 micro g of ciprofloxacin per ml. The frequency of decreased susceptibility was 7% (14 of 198) and was identical for the years 1991 and 1997. Serogroups...

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Source

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Identifiers

PMID: 12384345
DOI: 10.1128/AAC.46.11.3418-3421.2002
PMCID: PMC128732

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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