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Article

The chromatin-targeting protein Brd2 is required for neural tube closure and embryogenesis.

Biochimica et biophysica acta - 1 May 2009

Gyuris Aron, Donovan Diana J, Seymour Kimberly A, Lovasco Lindsay A, Smilowitz Nathaniel R, Halperin Anthony L P, Klysik Jan E, Freiman Richard N

Abstract excerpt

Chromatin modifications are essential for directing transcription during embryonic development. Bromodomain-containing protein 2 (Brd2; also called RING3 and Fsrg1) is one of four BET (bromodomain and extra-terminal domain) family members known to selectively bind acetylated histones H3 and H4. Brd2 associates with multiple subunits of the transcriptional apparatus including the mediator, TFIID and Swi/Snf...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19362612
DOI: 10.1016/j.bbagrm.2009.03.005
PMCID: PMC2740724

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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