Article

BRG1 establishes the neuroectodermal chromatin landscape to restrict dorsal cell fates

2023-06-24

Abstract excerpt

<h4>SUMMARY</h4> Cell fate decisions are achieved with gene expression changes driven by lineage-specific transcription factors (TFs). These TFs depend on chromatin remodelers including the BAF complex to activate target genes. BAF complex subunits are essential for development and frequently mutated in cancer. Thus, interrogating how BAF complexes contribute to cell fate decisions is critical for human health. W...

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Literature Corpus work: 416b92b9-3c82-59fc-8904-b5d2fa06a63d
DOI: 10.1101/2023.06.24.546365

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