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Article

Exaggerated aggression and decreased anxiety in mice deficient in brain serotonin.

Translational psychiatry - 29 May 2012

Mosienko V, Bert B, Beis D, Matthes S, Fink H, Bader M, Alenina N

Abstract excerpt

Serotonin is a major neurotransmitter in the central nervous system (CNS). Dysregulation of serotonin transmission in the CNS is reported to be related to different psychiatric disorders in humans including depression, impulsive aggression and anxiety disorders. The most frequently prescribed antidepressants and anxiolytics target the serotonergic system. However, these drugs are not effective in 20-30% of cases....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 22832966
DOI: 10.1038/tp.2012.44
PMCID: PMC3365263

Genes

TPH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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