Article

A simple method to dramatically increase <i>C. elegans</i> germline microinjection efficiency

2023-03-25

Abstract excerpt

Genome manipulation methods in C. elegans require microinjecting DNA or ribonucleoprotein complexes into the microscopic core of the gonadal syncytium. These microinjections are technically demanding and represent a key bottleneck for all genome engineering and transgenic approaches in C. elegans . While there have been steady improvements in the ease and efficiency of genetic methods for C. elegans genome mani...

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Literature Corpus work: 06e954a1-0f56-5d3e-82c6-600ff53b7415
DOI: 10.1101/2023.03.23.533855

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