Article
Amino acid metabolic origin as an evolutionary influence on protein sequence in yeast.
Journal of molecular evolution - 1 May 2009
de Bivort Benjamin L, Perlstein Ethan O, Kunes Sam, Schreiber Stuart L
Abstract excerpt
The metabolic cycle of Saccharomyces cerevisiae consists of alternating oxidative (respiration) and reductive (glycolysis) energy-yielding reactions. The intracellular concentrations of amino acid precursors generated by these reactions oscillate accordingly, attaining maximal concentration during the middle of their respective yeast metabolic cycle phases. Typically, the amino acids themselves are most abundant...
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