Article

Quantifying absolute gene expression profiles reveals distinct regulation of central carbon metabolism genes in yeast

2020-12-22

Abstract excerpt

In addition to specific regulatory circuits, gene expression is also regulated by global physiological cues such as the cell growth rate and metabolic parameters. Here we examine these global control mechanisms by analyzing an orthogonal multi-omics dataset consisting of absolute-quantitative abundances of the transcriptome, proteome, and intracellular amino acids in 22 steady-state yeast cultures. Our model indic...

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Literature Corpus work: ad1e0b19-116c-56f5-9076-c7d0518ade4a
DOI: 10.1101/2020.12.22.423946

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