Article

The amino acid composition of a protein influences its expression

2023-03-29

Abstract excerpt

The quantity of each protein in a cell only is only partially correlated with its gene transcription rate. Independent influences on protein synthesis levels include mRNA sequence motifs, amino acyl-tRNA synthesis levels, elongation factor action, and protein susceptibility to degradation. Here we report two novel forms of interaction between the amino acid composition of a protein and its expression level. In ani...

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Identifiers and source

Literature Corpus work: 37bfd85d-0d66-5a8e-b5e2-04da54b50d9d
DOI: 10.1101/2023.03.28.534610

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