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Article

Nucleotide bias causes a genomewide bias in the amino acid composition of proteins.

Molecular biology and evolution - 1 Nov 2000

Singer G A, Hickey D A

Abstract excerpt

We analyzed the nucleotide contents of several completely sequenced genomes, and we show that nucleotide bias can have a dramatic effect on the amino acid composition of the encoded proteins. By surveying the genes in 21 completely sequenced eubacterial and archaeal genomes, along with the entire Saccharomyces cerevisiae genome and two Plasmodium falciparum chromosomes, we show that biased DNA encodes biased...

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PMID: 11070046
DOI: 10.1093/oxfordjournals.molbev.a026257

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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