Article
Linking post-translational modifications and variation of phenotypic traits.
Molecular & cellular proteomics : MCP - 1 Mar 2013
Albertin Warren, Marullo Philippe, Bely Marina, Aigle Michel, Bourgais Aurélie, Langella Olivier, Balliau Thierry, Chevret Didier, Valot Benoît, da Silva Telma, Dillmann Christine, de Vienne Dominique, Sicard Delphine
Abstract excerpt
Enzymes can be post-translationally modified, leading to isoforms with different properties. The phenotypic consequences of the quantitative variability of isoforms have never been studied. We used quantitative proteomics to dissect the relationships between the abundances of the enzymes and isoforms of alcoholic fermentation, metabolic traits, and growth-related traits in Saccharomyces cerevisiae. Although the...
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