Article
Liver X receptor beta with mutations in the activation function-2 region is excluded from the nucleolus.
Cell biology international - 1 Mar 2009
Lall Rajuli, Kuruvilla Sarah, Prüfer Kirsten
Abstract excerpt
Liver X receptors (LXRs) alpha and beta are ligand-induced transcription factors that regulate transcription of genes encoding key regulators of cholesterol metabolism and transport, and of lipogenesis. Despite their high similarity, LXRalpha is the functionally dominant LXR isotype in the liver....
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