Article
Genetic evidence that formins function within the nucleus.
The Journal of biological chemistry - 20 Sept 1996
Chan D C, Leder P
Abstract excerpt
The murine limb deformity (ld) locus encodes a set of proteins, termed formins, that are required for embryonic limb and kidney development. Previous studies had indicated that these proteins are located in the nucleus and cytoplasm and have biochemical properties consistent with an action within...
Topics
- Abnormalities, Multiple
- Alleles
- Amino Acid Sequence
- Animals
- Bone and Bones
- Cell Compartmentation
- Cell Nucleus
- Fetal Proteins
- Formins
- Limb Deformities, Congenital
- Mice
- Microfilament Proteins
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Peptide Fragments
- Phenotype
- Sequence Deletion