Article
Minireview: liver X receptor beta: emerging roles in physiology and diseases.
Molecular endocrinology (Baltimore, Md.) - 1 Feb 2009
Gabbi Chiara, Warner Margaret, Gustafsson Jan-Ake
Abstract excerpt
Liver X receptors, LXRalpha and LXRbeta, are nuclear receptors belonging to the large family of transcription factors. After activation by oxysterols, LXRs play a central role in the control of lipid and carbohydrate metabolism as well as inflammation. The role of LXRalpha has been extensively studied, particularly in the liver and macrophages. In the liver it prevents cholesterol accumulation by increasing bile...
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