Article
The long amino-terminal tail domain of annexin XI is necessary for its nuclear localization.
Archives of biochemistry and biophysics - 1 Apr 1995
Mizutani A, Watanabe N, Kitao T, Tokumitsu H, Hidaka H
Abstract excerpt
Annexin XI is a newly identified annexin which localizes mainly in the nucleus of rat embryonic fibroblasts. There are no typical nuclear localization signals (NLS) in the molecule. To define the region responsible for its nuclear localization, a series of mutants and chimeric cDNA were constructed. These were transiently expressed in COS-7 cells, and the subcellular distributions of the mutants and chimeric...
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