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Article

Nuclear localization of liver X receptor alpha and beta is differentially regulated.

Journal of cellular biochemistry - 1 Jan 2007

Prüfer Kirsten, Boudreaux Jeanne

Abstract excerpt

Activity of nuclear receptors is regulated by their nuclear localization. Liver X receptors (LXR) alpha and beta are nuclear receptors that regulate transcription of genes for cholesterol metabolism, cholesterol transport, and lipogenesis. While LXR alpha and beta are very similar in structure and exhibit similar ligand binding properties, their physiological roles are quite different. Since the LXRs fall into a...

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Identifiers

PMID: 16888799
DOI: 10.1002/jcb.21006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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