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Article

Impact of novel PTEN mutations in Turkish patients with glioblastoma multiforme.

Journal of neuro-oncology - 1 May 2007

Tunca Berrin, Bekar Ahmet, Cecener Gulsah, Egeli Unal, Vatan Ozgur, Tolunay Sahsine, Kocaeli Hasan, Aksoy Kaya

Abstract excerpt

Glioblastoma multiforme (GBM) represents the most common and aggressive type of primary neoplasms of the central nervous system. The PTEN (phosphatase, tensin homologue, deleted on chromosome TEN; MIM # 601728) tumor suppressor gene has an essential biological role in the formation of glioblastomas. It is known that there are variations in genetic alterations in tumors that develop in patients with different...

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Source

Identifiers

PMID: 17151929
DOI: 10.1007/s11060-006-9293-z

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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