Article
Contribution of IL23R but not ATG16L1 to Crohn's disease susceptibility in Koreans.
Inflammatory bowel diseases - 1 Sept 2009
Yang Suk-Kyun, Park Miseon, Lim Jiyoung, Park Sang Hyoung, Ye Byong Duk, Lee Inchul, Song Kyuyoung
Abstract excerpt
BACKGROUND: Recent genome-wide association studies in Caucasian populations identified IL23R and ATG16L1 as susceptibility genes to Crohn's disease (CD). We tested 5 IL23R single nucleotide polymorphisms (SNPs) and 12 ATG16L1 SNPs in Korean patients to determine whether these genes are associated with susceptibility to CD in a non-Caucasian population. METHODS: We analyzed 5 IL23R SNPs and 12 ATG16L1 SNPs in 380...
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