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Article

Role of ATG16L, NOD2 and IL23R in Crohn's disease pathogenesis.

World journal of gastroenterology - 7 Feb 2012

Naser Saleh A, Arce Melissa, Khaja Anam, Fernandez Marlene, Naser Najih, Elwasila Sammer, Thanigachalam Saisathya

Abstract excerpt

Inflammatory bowel disease is a group of diseases that includes Crohn's disease (CD) and ulcerative colitis. CD is characterized as a chronic inflammatory disease of the gastrointestinal tract, ranging from the mouth to the anus. Although there are gross pathological and histological similarities between CD and Johne's disease of cattle, the cause of CD remains controversial. It is vital to understand fully the...

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Source

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Identifiers

PMID: 22346247
DOI: 10.3748/wjg.v18.i5.412
PMCID: PMC3270503

Genes

NOD2
CTLA4
TNFSF15

Provenance

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