Article
Appreciating HIV type 1 diversity: subtype differences in Env.
AIDS research and human retroviruses - 1 Mar 2009
Lynch Rebecca M, Shen Tongye, Gnanakaran S, Derdeyn Cynthia A
Abstract excerpt
Human immunodeficiency virus type 1 (HIV-1) group M is responsible for the current AIDS pandemic and exhibits exceedingly high levels of viral genetic diversity around the world, necessitating categorization of viruses into distinct lineages, or subtypes. These subtypes can differ by around 35% in the envelope (Env) glycoproteins of the virus, which are displayed on the surface of the virion and are targets for...
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