Implications of HIV diversity for the HIV-1 pandemic.

doi:10.1016/j.jinf.2012.10.026

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Article

Implications of HIV diversity for the HIV-1 pandemic.

The Journal of infection - 1 May 2013

Hemelaar Joris

Abstract excerpt

HIV-1 genetic variability within individuals and populations plays a central role in the HIV pandemic. Multiple zoonotic transmissions of SIV to humans have resulted in distinct HIV lineages in humans which have further diversified within the population over time. High rates of mutation and recombination during HIV reverse transcription create a genetic diversity in the host which is subject to selection...

Topics

Genetic Variation
HIV Infections
HIV-1
Humans
Pandemics

Source

Open in PubMed

Identifiers

PMID: 23103289
DOI: 10.1016/j.jinf.2012.10.026

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