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Article

Using HIV-1 sequence variability to explore virus biology.

Virus research - 1 Aug 2001

McGrath K M, Hoffman N G, Resch W, Nelson J A, Swanstrom R

Abstract excerpt

Human immunodeficiency virus type 1 (HIV-1) only recently established an epidemic world-wide infection in the human population. The virus persists in the human host through active replication and is able to avoid clearance by the immune system. Active replication is an important component of the rapid evolutionary potential of HIV-1, a potential which manifests itself in the evolution of immune escape variants,...

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PMID: 11410314
DOI: 10.1016/s0168-1702(01)00271-4

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