Article
Antibodies Targeting the Envelope of HIV-1.
Microbiology spectrum - 1 Feb 2015
Mayr Luzia M, Zolla-Pazner Susan
Abstract excerpt
Antibodies (Abs) are a critical component of the human immune response against viral infections. In HIV-infected patients, a robust Ab response against the virus develops within months of infection; however, due to numerous strategies, the virus usually escapes the biological effects of the various Abs. Here we provide an overview of the different viral evasion mechanisms, including glycosylation, high mutation...
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