Article
The origin and diversity of the HIV-1 pandemic.
Trends in molecular medicine - 1 Mar 2012
Hemelaar Joris
Abstract excerpt
This review examines the enormous progress that has been made in the past decade in understanding the origin of HIV, HIV genetic variability, and the impact of global HIV diversity on the pandemic. Multiple zoonotic transmissions of simian immunodeficiency virus (SIV) have resulted in different HIV lineages in humans. In addition, the high mutation and recombination rates during viral replication result in a...
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