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Article

Impact of genetic diversity of HIV-1 on diagnosis, antiretroviral therapy & vaccine development.

The Indian journal of medical research - 1 Apr 2005

Lal Renu B, Chakrabarti Sekhar, Yang Chunfu

Abstract excerpt

HIV-1 strains have diversified extensively through mutation and recombination since their initial transmission to human beings many decades ago in central Africa. The high error rate of HIV reverse transcriptase combined with the estimated in vivo HIV-1 replication rate of ten billion new virions each day leads to extraordinary genetic diversity of HIV. Twenty seven circulating genetic forms of the HIV-1 group M...

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PMID: 15817945

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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