Article
Asynchronous replication and autosome-pair non-equivalence in human embryonic stem cells.
PloS one - 1 Jan 2009
Dutta Devkanya, Ensminger Alexander W, Zucker Jacob P, Chess Andrew
Abstract excerpt
A number of mammalian genes exhibit the unusual properties of random monoallelic expression and random asynchronous replication. Such exceptional genes include genes subject to X inactivation and autosomal genes including odorant receptors, immunoglobulins, interleukins, pheromone receptors, and p120 catenin. In differentiated cells, random asynchronous replication of interspersed autosomal genes is coordinated...
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