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Article

Random replication of the inactive X chromosome.

Genome research - 1 Jan 2014

Koren Amnon, McCarroll Steven A

Abstract excerpt

In eukaryotic cells, genomic DNA replicates in a defined temporal order. The inactive X chromosome (Xi), the most extensive instance of facultative heterochromatin in mammals, replicates later than the active X chromosome (Xa), but the replication dynamics of inactive chromatin are not known. By profiling human DNA replication in an allele-specific, chromosomally phased manner, we determined for the first time...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosomes, Human, X

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Share to X Chromosome Inactivation

Source

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Identifiers

PMID: 24065775
DOI: 10.1101/gr.161828.113
PMCID: PMC3875862

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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