Genetics in rheumatoid arthritis beyond HLA genes: what meta-analyses have shown?

doi:10.1016/j.semarthrit.2012.12.003

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Article

Genetics in rheumatoid arthritis beyond HLA genes: what meta-analyses have shown?

Seminars in arthritis and rheumatism - 1 Aug 2013

Chatzikyriakidou Anthoula, Voulgari Paraskevi V, Lambropoulos Alexandros, Drosos Alexandros A

Abstract excerpt

OBJECTIVE: Rheumatoid arthritis (RA) is a complex disorder with many genetic and environmental factors to account for disease susceptibility. Individual genetic association studies usually suffer from small sample size leading to biased results of polymorphisms association with RA liability. Therefore, meta-analyses seem to resolve this limitation, up to a point, increasing the power of statistical analyses. In...

Topics

Arthritis, Rheumatoid
Genetic Predisposition to Disease
Genotype
HLA Antigens
Humans
Meta-Analysis as Topic
Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 23768941
DOI: 10.1016/j.semarthrit.2012.12.003

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