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Article

Novel variants of the human flavin-containing monooxygenase 3 (FMO3) gene associated with trimethylaminuria.

Molecular genetics and metabolism - 1 Jun 2009

Motika Meike S, Zhang Jun, Zheng Xueying, Riedler Kiersten, Cashman John R

Abstract excerpt

The disorder trimethylaminuria (TMAu) often manifests itself in a body odor for individuals affected. TMAu is due to decreased metabolism of dietary-derived trimethylamine (TMA). In a healthy individual, 95% or more of TMA is converted by the flavin-containing monooxygenase 3 (FMO3, EC 1.14.13.8) to non-odorous trimethylamine N-oxide (TMA N-oxide). Several single nucleotide polymorphisms (SNPs) of the FMO3 gene...

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Source

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Identifiers

PMID: 19321370
DOI: 10.1016/j.ymgme.2009.02.006
PMCID: PMC2739593

Genes

FMO3
DPT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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