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Article

Trimethylaminuria is caused by mutations of the FMO3 gene in a North American cohort.

Molecular genetics and metabolism - 1 Sept 1999

Akerman B R, Lemass H, Chow L M, Lambert D M, Greenberg C, Bibeau C, Mamer O A, Treacy E P

Abstract excerpt

Trimethylaminuria (TMAuria) (McKusick 602079) first described in 1970 is an autosomal recessive condition caused by a partial or total incapacity to catalyze the N-oxygenation of the odorous compound trimethylamine (TMA). The result is a severe body odor and associated psychosocial conditions. This inborn error of metabolism, previously thought to be rare, is now being increasingly detected in severe and milder...

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Source

Identifiers

PMID: 10479479
DOI: 10.1006/mgme.1999.2885

Genes

FMO3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Trimethylaminuria is caused by mutations of the FMO3 gene in a North American cohort.PMID 10479479Read ↗

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