Human flavin-containing monooxygenase form 3: cDNA expression of the enzymes containing amino acid substitutions observed in individuals with trimethylaminuria.

doi:10.1021/tx9700533

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Article

Human flavin-containing monooxygenase form 3: cDNA expression of the enzymes containing amino acid substitutions observed in individuals with trimethylaminuria.

Chemical research in toxicology - 1 Aug 1997

Cashman J R, Bi Y A, Lin J, Youil R, Knight M, Forrest S, Treacy E

Abstract excerpt

Trimethylaminuria is an autosomal recessive human disorder affecting a small part of the population as an inherited polymorphism. Individuals diagnosed with trimethylaminuria excrete relatively large amounts of trimethylamine in their urine, sweat, and breath, and this results in a fishy odor cha...

Topics

DNA, Complementary
Humans
Metabolism, Inborn Errors
Methylamines
Mutation
Odorants
Oxygenases
Structure-Activity Relationship

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