Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Trimethylaminuria and a human FMO3 mutation database.

Human mutation - 1 Sept 2003

Hernandez Diana, Addou Sarah, Lee David, Orengo Christine, Shephard Elizabeth A, Phillips Ian R

Abstract excerpt

Trimethylaminuria (TMAuria), or fish-odor syndrome, is due to defective flavin-containing monooxygenase 3 (FMO3). In the liver, this protein catalyzes the NADPH-dependent oxidative metabolism of odorous trimethylamine (TMA), derived in the gut from dietary sources, to nonodorous trimethylamine N-oxide (TMA N-oxide). Affected individuals are unable to carry out this reaction and consequently exude a fishy body...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Databases, Genetic
Share to FMO3 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Metabolism, Inborn Errors

Share to Methylamines

Share to Mutation

Share to Oxygenases

Source

Identifiers

PMID: 12938085
DOI: 10.1002/humu.10252

Genes

FMO3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Trimethylaminuria and a human FMO3 mutation database.PMID 12938085Read ↗

A spectrum of molecular variation in a cohort of Italian families with trimethylaminuria: identification of three novel mutations of the FM03 gene.Semantic proximity Read ↗

Trimethylaminuria (fish odor syndrome): genotype characterization among Portuguese patients.Semantic proximity Read ↗

Trimethylaminuria is caused by mutations of the FMO3 gene in a North American cohort.Semantic proximity Read ↗

Novel variants of the human flavin-containing monooxygenase 3 (FMO3) gene associated with trimethylaminuria.Semantic proximity Read ↗

Missense mutation in flavin-containing mono-oxygenase 3 gene, FMO3, underlies fish-odour syndrome.Semantic proximity Read ↗

Biochemical and clinical aspects of the human flavin-containing monooxygenase form 3 (FMO3) related to trimethylaminuria.Semantic proximity Read ↗

Genetic polymorphism of the flavin-containing monooxygenase 3 (FMO3) associated with trimethylaminuria (fish odor syndrome): observations from Japanese patients.Semantic proximity Read ↗

Mutation, polymorphism and perspectives for the future of human flavin-containing monooxygenase 3.Semantic proximity Read ↗

Survey of variants of human flavin-containing monooxygenase 3 (FMO3) and their drug oxidation activities.Semantic proximity Read ↗

Deleterious mutations in the flavin-containing monooxygenase 3 (FMO3) gene causing trimethylaminuria.Semantic proximity Read ↗

Fish odor syndrome (trimethylaminuria) supporting the possible FMO3 down expression in childhood: a case report.Semantic proximity Read ↗

Variants in the flavin-containing monooxygenase 3 (FMO3) gene responsible for trimethylaminuria in a Japanese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.