Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Biochemical and clinical aspects of the human flavin-containing monooxygenase form 3 (FMO3) related to trimethylaminuria.

Current drug metabolism - 1 Apr 2003

Cashman John R, Camp Kathryn, Fakharzadeh Steven S, Fennessey Paul V, Hines Ronald N, Mamer Orval A, Mitchell Steven C, Nguyen George Preti, Schlenk Daniel, Smith Robert L, Tjoa Susan S, Williams David E, Yannicelli Steven

Abstract excerpt

Trimethylaminuria is a rare metabolic disorder that is associated with abnormal amounts of the dietary-derived trimethylamine. Excess unmetabolized trimethylamine in the urine, sweat and other body secretions confers a strong, foul body odor that can affect the individual's ability to work or engage in social activities. This review summarizes the biochemical aspects of the condition and the classification of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clinical Trials as Topic
Share to Diet

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hypertension

Share to Metabolic Diseases

Share to Metabolism, Inborn Errors

Share to Methylamines

Share to Odorants

Share to Oxygenases

Source

Identifiers

PMID: 12678693
DOI: 10.2174/1389200033489505

Genes

FMO3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Biochemical and clinical aspects of the human flavin-containing monooxygenase form 3 (FMO3) related to trimethylaminuria.PMID 12678693Read ↗

Trimethylaminuria.Semantic proximity Read ↗

Novel variants of the human flavin-containing monooxygenase 3 (FMO3) gene associated with trimethylaminuria.Semantic proximity Read ↗

Trimethylaminuria and a human FMO3 mutation database.Semantic proximity Read ↗

Trimethylamine and Trimethylamine N-Oxide, a Flavin-Containing Monooxygenase 3 (FMO3)-Mediated Host-Microbiome Metabolic Axis Implicated in Health and DiseaseSemantic proximity Read ↗

Relationships between flavin-containing mono-oxygenase 3 (FMO3) genotype and trimethylaminuria phenotype in a Japanese population.Semantic proximity Read ↗

Genetic variants of flavin-containing monooxygenase 3 (FMO3) in Japanese subjects identified by phenotyping for trimethylaminuria and found in a database of genome resources.Semantic proximity Read ↗

In vivo variability of TMA oxidation is partially mediated by polymorphisms of the FMO3 gene.Semantic proximity Read ↗

Fish odor syndrome (trimethylaminuria) supporting the possible FMO3 down expression in childhood: a case report.Semantic proximity Read ↗

Trimethylaminuria is caused by mutations of the FMO3 gene in a North American cohort.Semantic proximity Read ↗

Mutations of the flavin-containing monooxygenase gene (FMO3) cause trimethylaminuria, a defect in detoxication.Semantic proximity Read ↗

Deleterious mutations in the flavin-containing monooxygenase 3 (FMO3) gene causing trimethylaminuria.Semantic proximity Read ↗

Functional characterization of genetic variants of human FMO3 associated with trimethylaminuria.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.