Article
Advanced intercross line mapping suggests that ncf1 (ean6) regulates severity in an animal model of guillain-barre syndrome.
Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2009
Huberle Alexander, Beyeen Amennai Daniel, Ockinger Johan, Ayturan Miriam, Jagodic Maja, de Graaf Katrien L, Fissolo Nicolas, Marta Monica, Olofsson Peter, Hultqvist Malin, Holmdahl Rikard, Olsson Tomas, Weissert Robert
Abstract excerpt
We here present the first genetic fine mapping of experimental autoimmune neuritis (EAN), the animal model of Guillain-Barré syndrome, in a rat advanced intercross line. We identified and refined a total of five quantitative trait loci on rat chromosomes 4, 10, and 12 (RNO4, RNO10, RNO12), showin...
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