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Article

Advanced intercross line mapping of Eae5 reveals Ncf-1 and CLDN4 as candidate genes for experimental autoimmune encephalomyelitis.

Journal of immunology (Baltimore, Md. : 1950) - 15 May 2006

Becanovic Kristina, Jagodic Maja, Sheng Jian Rong, Dahlman Ingrid, Aboul-Enein Fahmy, Wallstrom Erik, Olofsson Peter, Holmdahl Rikard, Lassmann Hans, Olsson Tomas

Abstract excerpt

Eae5 in rats was originally identified in two F(2) intercrosses, (DA x BN) and (E3 x DA), displaying linkage to CNS inflammation and disease severity in experimental autoimmune encephalomyelitis (EAE), respectively. This region overlaps with an arthritis locus, Pia4, which was also identified in the (E3 x DA) cross. Two congenic strains, BN.DA-Eae5 and BN.DA-Eae5.R1, encompassing the previously described Eae5 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Encephalomyelitis, Autoimmune, Experimental

Share to Myelin-Associated Glycoprotein

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Source

Identifiers

PMID: 16670314
DOI: 10.4049/jimmunol.176.10.6055

Genes

CLDN4
MOG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Advanced intercross line mapping of Eae5 reveals Ncf-1 and CLDN4 as candidate genes for experimental autoimmune encephalomyelitis.PMID 16670314Read ↗

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