Article
The axon reaction: identifying the genes that make a difference.
Physiology & behavior - 10 Sept 2007
Piehl Fredrik, Swanberg Maria, Lidman Olle
Abstract excerpt
Numerous CNS diseases of primarily non-inflammatory origin, such as idiopathic neurodegenerative diseases, contain elements of inflammation, with T cell infiltration, MHC class II expression and neuron/axon damage. Gene mapping in human clinical materials have in most cases failed to unravel discrete genes, since most genes instrumental in non-Mendelian forms of these complex diseases are likely to modestly...
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