Article
An integrated genetic linkage map with 1,137 markers constructed from five F2 crosses of autoimmune disease-prone and -resistant inbred rat strains.
Genomics - 15 Jan 2000
Dracheva S V, Remmers E F, Chen S, Chang L, Gulko P S, Kawahito Y, Longman R E, Wang J, Du Y, Shepard J, Ge L, Joe B, Kotake S, Salstrom J L, Furuya T, Hoffman J, Cannon G W, Griffiths M M, Wilder R L
Abstract excerpt
The rat (Rattus norvegicus) is an important experimental model for many human diseases including arthritis, diabetes, and other autoimmune and chronic inflammatory diseases. The rat genetic linkage map, however, is less well developed than those of mouse and human. Integrated rat genetic linkage maps have been previously reported by Pravenec et al. (1996, Mamm. Genome 7: 117-127) (500 markers mapped in one...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.