Article
Shh dependent and independent maintenance of basal midbrain.
Mechanisms of development - 1 Jan 2000
Perez-Balaguer Ariadna, Puelles Eduardo, Wurst Wolfgang, Martinez Salvador
Abstract excerpt
Sonic hedgehog (Shh) is well known as the molecule responsible for the induction and maintenance of ventral neural tube structures. Recent data have shown that ventral neuronal populations react differentially to the amount of this morphogen not only in the spinal cord, but also in more rostral parts of the brain, like the midbrain. A dorsal expansion in the Shh expression domain modifies the differentiation...
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